Summary

Published Date: March 01, 2025

Researchers investigate the association between nativity and COVID-19 vaccine acceptance and its interaction with race/ethnicity, education, and English proficiency.

Differences in vaccine acceptance among propensity-score matched foreign- and U.S.-born persons using 2021 California Health Interview Survey Data were measured using a survey-weighted multivariable logistic regression model with interaction terms and average predicted probabilities between nativity and: race/ethnicity, education, English proficiency.

Findings: A total of 4,234,655 survey-weighted persons (8,504 unweighted) met inclusion criteria; 2,251,279 (53 %) were foreign-born (1,983,376 US-born), and 55 % of all persons were Hispanic/Latino, 22% were Non-Hispanic white, 17 % were Non-Hispanic Asian/Pacific Islander, 3.6 % were Non-Hispanic Black/African American, and 2.5% were categorized as ‘Other.’ Foreign-born status was significantly associated with greater odds of acceptance. Foreign-born Hispanic persons had a significantly greater probability of acceptance compared to their U.S.-born counterparts. Foreign-born persons with poor English proficiency had a lower probability of acceptance versus U.S.-born persons.

Nativity was significantly associated with COVID-19 vaccine acceptance, and this relationship varied by race/ethnicity and English proficiency. These findings may be used to direct future interventions aimed at improving COVID-19 vaccination rates.